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Author Topic: ACTC NEWS !
Livinonklendathu
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Me thinks that QUIN is the ax - any takers?

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......in Psychiatry circles it's known as a "warning sign"

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ctguy13
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1.83 wall? Let's see if it's made of brick or paper!
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T e x
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Who *is* watching L2s? jumping around quite a bit?

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Nashoba Holba Chepulechi
Adventures in microcapitalism...

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Repoman75
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Too volatile today, have to wait for EOD action... probably will gap again tomorrow if they sell off today.

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Stick with Repo's plan in '07 - FRPT/DKAM!

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T e x
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c'mon, piggy...PUSH!

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Nashoba Holba Chepulechi
Adventures in microcapitalism...

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ctguy13
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Paper! We have a winner!
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T e x
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some nice lil spanks, there...

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Nashoba Holba Chepulechi
Adventures in microcapitalism...

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ctguy13
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Gettin' jiggy!
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Ace of Spades
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Wednesday, Aug. 23, 2006

End Run Around the Stem-Cell Ban?

As we've noted many times, scientists looking to develop stem cells into powerful therapies against an enormous number diseases ranging from diabetes to Parkinson's have been utterly frustrated by the Bush Administration's ban on federal funding. According to that policy, they can only use federal dollars on the handful of stem cell lines in existence at the time Bush's policy went into effect in 2001--a pitifully small, very finicky source.

So far, scientists have responded in several ways. Some are trying to use adult stem cells, which may or may not turn out to be effective; others are using the state funding that's arisen in response to Bush's policy; still others have just given up and gone to countries, like China or Singapore or Britain, that have a more enlightened policy.

But a little more than an hour ago, the American company Advanced Cell Technology reported in Nature that they may have a way to start up stem cell lines in a new way that could ultimately make non-federal research easier. By taking a single cell out of the seven or eight that make up an embryo at its earliest stages, they've left the embryo intact but managed to create stem cells from the one they removed. No embryo is destroyed in the process, which is one of the key no-no's in the Bush policy.

It's actually not news that you can safely remove a cell from an embryo. It's done all the time in a procedure called pre-implantation genetic diagnosis. The idea is that parents known to be carrying a potentially dangerous gene--for Tay-Sachs disease, say--do in-vitro (a.k.a. test tube) fertilization. One cell is removed, it's tested for genetic problems, and if there are none, the embryo is implanted and fertilization goes ahead.

So scientists at ACT took a cell and tried to coax it into becoming a stem cell colony. Turned out it wasn't so easy, and in the end they had to use "feeder cells" from mice to nourish the human cells, and add other human stem cells to coax them to grow. That introduces contamination that makes the new line essentially useless for potential therapies. Dr. Robert Lanza, who did the research, thinks they can overcome these crutches: the embryos they used were frozen specimens that had been originally created for preimplantation diagnosis; fresh embryos might well be easier to work with. And while other scientists are very cautious about a full-fledged endorsement before others have replicated ACT's work, Dr. Arnold Kriegstein of the University of San Francisco’s Institute for Regeneration Medicine says: “It looks quite impressive. If it holds up, I think it has the promise of being a very significant advance in the field.”

Important note: this entry is based on reporting by Alice Park

—M.L.

http://time.****s.com/eye_on_science/2006/08/end_run_around_.html

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bksundar
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People already getting fed up with this stock.
I really thought this will almost reach $3 in the morning before re-tracing to the 2s...

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Ace of Spades
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Embryonic stemcells: New research seeks to ease ethical storm
Posted: 24 August 2006 2154 hrs

PARIS : New research into embryonic stem cells has sought to ease the ethical storm, fiercest in the United States, that swirls
around a revolutionary but still untested technology for reversing degenerative disease.

Stemcells are immature cells that grow into various tissues. The most exciting of these types are so-called pluripotent stemcells that are garnered from embryos at a very early stage and develop into almost any kind of tissue.

The dream of scientists -- and of investors who have pumped hundreds of millions of dollars into the research -- is to coax embryonic stemcells into become lab-dish replacements for cells that have been damaged or destroyed by cancer, Alzheimer's, Parkinson's and other diseases.

So far, the quest has proven to be a greater technical challenge than was thought and it has been rocked by ethical debate, particularly in the United States, over embryos as the source of these powerful cells.

But American researchers, in a study published on Thursday in the British science journal Nature, believe they have found a way out of the dilemma by using a technique that does not kill the embyro.

Advanced Cell Technology, a biotech firm in Alameda, California, said it had found a way to grow lines of stem cells from a single cell extracted from an embryo.

The team adapted an existing method called pre-implantation diagnosis (PGD).

Under PGD, doctors take a single cell from an embryo and screen its genome for telltale signs of inherited disorders, thus giving parents the possibility of an abortion to spare the child a life that could be short or crippled.

After successfully testing their theory on lab mice, the US researchers took a single cell from a cluster of eight-to-10 cells that comprises an early embryos used for stemcells.

Of 16 spare embryos on which they used this technique, the team extracted 91 cells, two of which developed into lines of stemcells that have grown continuously in the lab for eight months.

Tests have shows that the cells are just like ordinary embryonic stem cells.

"These cell lines were genetically normal and retained their potential to form all of the cells of the human body, including nerve, liver, blood, vascular and retinal cells that could potentially be used to treat a range of human diseases," the study says.

The head of the team, Bob Lanza, hopes the breakthrough will prompt US President George W. Bush to lift his veto on the use of federal funds for embryonic stem-cell research.

"We need to jump-start the field, it's been crippled by a lack of funding," said Lanza. "This will hopefully solve the political impasse and bring the president on board, as no embryos will be harmed with this method."

Embryonic stem-cell research in the United States still attracts private financing and federal funds are available for self-replicating stem-cell lines that existed before Bush took office. But the lack of federal support has had a big impact.

Only last month, Bush warned he would not retreat, wielding his first veto in five and a half years in office to annul a bill that would expand government funding for stem-cell research.

He blasted the bill as backing "the taking of innocent human life in the hope of finding medical benefits for others. It crosses a real moral boundary that our society needs to respect".

Lanza met with applause Thursday for his technical prowess, but also caution for his claims.

Ian Wilmut, the British scientist who led the team that created Dolly the Sheep in 1996, said Lanza had derived only two stem-cell lines out of 91 cells, and further work was needed to boost the success rate to make the method useful.

Robin Lovell-Badge of Britain's National Institute for Medical Research, agreed. The chief beneficiaries could be couples who underwent PGD in order to have a stem-cell line matched to a child for future therapeutic use, he said.

"I am also unconvinced by the ethical arguments," said Lovell-Badge. "Spare IVF embryos used to derive stem-cell lines would have been destroyed anyway."

Alison Murdoch of the International Centre for Life, a bioscience and educational institute in Newcastle, northeastern England, said embryos conceived through in-vitro fertilisation and had been screened by PGD had grown into normal bodies.

"However, it is not true to say the biopsy is not detrimental to the embryos. Some embryos do not survive," the website of New Scientist (newscientist.com) quoted Murdoch as saying.

http://www.channelnewsasia.com/stories/health/view/226655/1/.html

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doling2005
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Well, I predicted 12 million in volume yesterday and we're already there. First 6 million in selling and the last 6 million in buying
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neona
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Is this ever gonna get $2 ?

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New to the game... but I'm a quick learner.

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ctguy13
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I bet the White House will have correspondents on the conference call tomorrow...
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Repoman75
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Yep, news conf. will be huge.

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Stick with Repo's plan in '07 - FRPT/DKAM!

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Ace of Spades
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Stem cell find may shift debate
Email Print Normal font Large font Hard cell … Bob Carr and Natasha Stott Despoja.

August 25, 2006

A BREAKTHROUGH in stem cell research in the US, which allows a single stem cell to be removed from embryos without destroying them, may dramatically shift the ethical debate in Australia.

The US development drew conflicting responses from federal MPs yesterday over its significance to proposed Australian legislation to lift the ban on stem cell research that requires the destruction of the embryo.

Opponents of the legislation, including the Minister for Health, Tony Abbott, welcomed the development. It appeared "to offer the prospect of ethical research," he said.

"And if it's all true, it suggests to me that the whole debate we are about to have over changing the law to allow cloning might be unnecessary," said Mr Abbott whose views were echoed by other opponents of cloning.

But a Liberal MP, Mal Washer, who has led the campaign for legislative change, described the latest development as a furphy.

He said that as result of the recommendations by the expert Lockhart review, the Australian debate was about the transfer of cells into an unfertilised human egg for the purposes of producing embryonic stem cells. The US research involved the use of cells from embryos created from sperm and eggs - a process already allowed in Australia with surplus IVF embryos.

Parliament authorised the use of surplus IVF embryos in 2002.

Outside a roundtable discussion organised by the Democrats senator Natasha Stott Despoja in Sydney yesterday, Professor Ian Kerridge and Professor Peter Schofield, members of the Lockhart inquiry, explained why the US research was significant.

"The research is quite an important breakthrough. In this instance a sperm and egg embryo has had one of its cells removed and that cell has been used to derive embryonic stem cells, then allowing the embryo to go and develop normally," Professor Peter Schofield said.

"That research that has been reported in America is not currently permitted in Australia under our legislation.

"We would need to accept some of the Lockhart recommendations to allow a licence to be issued for this type of research … because it would require sperm and egg embryos to be created specifically for research."

However, Professor Ian Kerridge warned that this process was not without risk to the embryo. He said it would be unwise to implant an embryo that had had a cell removed into a woman, allowing it to develop into a child.

Senator Stott Despoja said she had almost completed a draft of a private members bill implementing the Lockhart review findings and hoped to put a draft before Parliament next month. The former health minister Senator Kay Patterson is also working on a private member's bill.

Asked whether her efforts could dovetail with those of Senator Patterson, Senator Stott Despoja said it was imperative they all work together.

Federal Parliament was expected to debate legislation to lift the ban on therapeutic cloning - a technique that does not involve fertilised embyros - next month.

http://www.smh.com.au/news/national/stem-cell-find-may-shift-debate/2006/08/24/1 156012675614.html

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BangYa
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I am hoping it hits 3 by the end of day, but by the way it looks it might not make it [Frown] I got in at the high end this morning.
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Mysticobra96
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Yeah I think this will be a good eod buy.
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Ace of Spades
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Lib Senator welcomes new stem cell research

AM - Thursday, 24 August , 2006 08:04:00
Reporter: Samantha Hawley
TONY EASTLEY: One of the Federal Government's staunchest opponents of embryonic stem cell research for the therapeutic cloning technique has welcomed the groundbreaking research.

Liberal Senator Guy Barnett has backed the Health Minister Tony Abbott's fear that allowing the stem cell research in this country would be a slippery slope towards human cloning.

But Guy Barnett says he would seriously consider supporting the research if there was a guarantee the embryo could be saved.

He's been speaking to Samantha Hawley in Canberra.

GUY BARNETT: This type of research could occur here in Australia under the laws passed four years ago, which allows embryonic stem cell research in certain circumstances.

It highlights the opportunity and the possibility of avoiding, all together, the ethical issues raised by embryonic stem cell research, which under the proposals require the destruction of the human embryo.

That's good news, because it focuses on what needs to be considered, and that is the human embryo, and its life.

SAMANTHA HAWLEY: Okay, so this will then dispel all of your ethical objections?

GUY BARNETT: Well, if this research is subsequently proven, and of course we are unaware of the long-term effects and the health effects in any resulting children, because the researchers say that the embryo can then be used for IVF or for the purposes for sustaining life, so obviously it would need to be further concluded that there are no long-term health effects on any resulting children.

Of course, if you can remove the ethical objections regarding the destruction of the human embryo and the destruction of potential life, they are the very key ingredients to the ethical objections.

SAMANTHA HAWLEY: Well, you agree with the Health Minister Tony Abbot that embryonic stem cell research is a slippery slope towards human cloning, does that then dispel all your concerns about human cloning as well?

GUY BARNETT: No, it doesn't. It doesn't, sadly, because the human cloning is another matter. Every human being is independent and unique and special. Cloning is a creation of a copy, and that is certainly going down the wrong road.

SAMANTHA HAWLEY: Okay, but if there was a Bill before the Australian Parliament that would guaranteed that an embryo wouldn't be destroyed, you would support that.

GUY BARNETT: I would consider that very, very carefully, and I would hope that all members of Parliament would consider the merits of such a thing, where we can avoid the ethical issues of destroying a human embryo.

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Ace of Spades
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Joyce supportive of new stem cell research method

The World Today - Thursday, 24 August , 2006 12:18:00
Reporter: Samantha Hawley
ELEANOR HALL: The Nationals Senator Barnaby Joyce who earlier in the program said he could support stem cell research if the human embryo wasn't destroyed has just heard the comments from Professor Peter Schofield.

He's speaking to Samantha Hawley in Canberra.

BARNABY JOYCE: I acknowledge what Professor Schofield said, however, if you can get stem cells without killing the foetus, or the foetus wasn't specifically made for attaining those cells, then I still do not have an ethical problem with that.

The problem is when you kill a human life for the purpose of attaining material or parts.

SAMANTHA HAWLEY: But Professor Schofield says that in some regards this is more ethically worrying than the existing path.

BARNABY JOYCE: Well, I disagree. If you can attain the cells without killing the human embryo, the human being, then I do not have a problem with that, provided that the human was not created specifically for the attainment of spare parts.

If it is part of its life and it doesn't kill it, and that life can go on, then that is a completely different issue.

SAMANTHA HAWLEY: So, creating a sperm and egg embryo for research, you don't have an ethical problem with that.

BARNABY JOYCE: My ethical problem is in the killing of human life.

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T e x
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quote:
Originally posted by bksundar:
People already getting fed up with this stock.
I really thought this will almost reach $3 in the morning before re-tracing to the 2s...

disagree...traders had lottsa profit from yesterday...MMs not so much...they've been hopping all over, taking turns...eg, NITE was bidside 1.76, then 1.77, then 1.82....

What's your take, Deuce?

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Nashoba Holba Chepulechi
Adventures in microcapitalism...

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Mysticobra96
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Well I changed my chart to 5min instead of min/min and wow! I would have never bought when I did if I had looked at the 5 min chart. I think its much better for the bigger stocks. I use the min/min for pennies but Im going to use the 5 min for 1.00+ cuz its much more accurate. Hope it helps some others figure this nightmare of when to buy and sell out!
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Ace of Spades
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Bush Administration Invents New Excuse To Oppose Embryonic Stem Cell Research

http://thinkprogress.org/2006/08/24/bush-embryonic-stem-cells/

Stem cell advance challenges Bush

http://www.theaustralian.news.com.au/story/0,20867,20245019-30417,00.html

http://www.timesonline.co.uk/article/0,,3-2325877,00.html

[ August 24, 2006, 12:30: Message edited by: Ace of Spades ]

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Double Deuce
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quote:
Originally posted by T e x:
quote:
Originally posted by bksundar:
People already getting fed up with this stock.
I really thought this will almost reach $3 in the morning before re-tracing to the 2s...

disagree...traders had lottsa profit from yesterday...MMs not so much...they've been hopping all over, taking turns...eg, NITE was bidside 1.76, then 1.77, then 1.82....

What's your take, Deuce?

Clearly the MMs have been enjoying themselves today. [Smile] This news isn't going away folks.....too big an issue and it is the talk of the world today. This morning's action has been profit taking by the traders....imo

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It's all good.

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T e x
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i'll buy that...

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Nashoba Holba Chepulechi
Adventures in microcapitalism...

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bksundar
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Being run down to 1.60s....
I bought at 1.20

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Mysticobra96
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This stock is tuff because based on charts its a no brainer to sell. But this news could make it still run tomorrow. I think I'll have to wait till eod to make a decision.
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BLACKBEARD
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conferance call tommorrow too

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PREPARE TO BE BOARDED

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T e x
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1.79 coming?

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Nashoba Holba Chepulechi
Adventures in microcapitalism...

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Mysticobra96
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I think it might have 1.75 in it then back down.
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Jo4321
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Clearly this is a hot topic. Don't you all think that this will be hitting even the national evening news tonight? Could be setting up for a big gap in the am, especially with the conference call during the day.

Jo

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"Great Day for Up!"....Dr. Seuss

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IMAKEMONEY
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ok im in 1.69, do it!

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LIFE IS 10% HOW YOU MAKE IT AND 90% HOW YOU TAKE IT!

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neona
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What time tomorrow is the Press-Conference?

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New to the game... but I'm a quick learner.

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T e x
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quote:
Originally posted by Jo4321:
Clearly this is a hot topic. Don't you all think that this will be hitting even the national evening news tonight? Could be setting up for a big gap in the am, especially with the conference call during the day.

Jo

fresh news doubtful...

conference call may have some punch...

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Nashoba Holba Chepulechi
Adventures in microcapitalism...

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Mysticobra96
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I think its 12 EST.
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