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T O P I C     R E V I E W
only_biotech  - posted

DNAP - THE NEXT $50 BIOTECH STOCK?

WE THINK SO HERES WHY!!

Dnaprint (DNAP) is an emerging biotech company and is trading under $1 !!!

1) CEO (Dr. Tony Frudakis) Lead scientist for Corixa starts his own company a
few months ago

2) Company is formed by a reverse merger of a pinksheet company

3) DNAP has already completed the accounting to get off the pinksheets and
should be listed on the OTCBB soon.

4) Dr. Frudakis was responsible for a patent that sold for $54,000,000 to
Smith Kline Beecham while he was at Corixa.

5) Corixa's stock has gone from 14 Cents a few years ago to 50 Dollars today.

6) According to the Barron's article (9/25/00 pg 52), Dnaprint is in the late stages of forming
strategic alliances with major companies.


MAJOR WEB PAGES RELATED TO DNAP
dnap http://www.dnaprint.com/
orchid biosciences inc http://www.orchidbio.com/

INVEST IN DNAP
email for free investment package= hresources@dnaprint.com
or call 1-877-362-3453(toll free)
investment club web page=http://clubs.yahoo.com/clubs/dnaprintgenomicsinvestors
investors report= http://www.companyreporter.com/index.php?u=companies.php
great dnap investor links: http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=22034 http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=23118
http://cbs.marketwatch.com/news/current/molinski.htx?source=htx/http2_mw =invest in biotech http://www.loonycat.com/Genomics.htm =the human genome investors portal
clearstation rates danp http://www.clearstation.com/cgi-bin/details?Event=peek&Symbol=DNAP&Refer=http://www.purepennies.com/
purepenny&3bagger rate dnap http://www.ragingbull.altavista.com/mboard/boards.cgi?board=PCBM&read=132938
Pennystockprofits assess dnap http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=15730
tipreporter rates dnap http://www.tipreporter.com/search.php?search=dnap
dnap on stocktribes hotlist for 21 weeks http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=24335
analysts tips and reports on dnap http://www.tipreporter.com/search.php?search=dnap http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=15730

why is dnap unique in the bio tech sector?? http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=22654

NEWSLINKS GENERAL FOR DNAP
dnap company news http://www.bell2bell.newsalert.com/bin/digest?Symbol=DNAP& =bell2bell news http://quicken.excite.com/investments/quotes/?s=DNAP&t=0 =excite news
http://biz.yahoo.com/n/D/DNAP.html =yahoo news
dnap in barrons http://www.sockthestocks.com/profiles/dnapbarrons.htm
bioinform news service http://www.bioinform.com/
online journal of bioinformatics http://www.cpb.uokhsc.edu/ojvr/xmlpaper.html#Sites

UPCOMING EVENTS RELATED TO DNAP
bio partnering Europe- London England-16-17 oct 2000 http://www.biopartnering.com/bpe/index.html
structural genomics conference-yokohama,japan,2-5nov2000 http://icsg2000.riken.go.jp/

TECHNICAL SITES RELATED TO DNAP
dnap patents http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=21559
dnap is about pharmacogentics http://www.nigms.nih.gov/funding/medforyou.html
stem cell research http://www.stemcellresearchnews.com/index.html
personalized medicine no longer science fiction http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=25033
safe drugs that fit like a glove http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=11203

NEW STAFF ARRIVING AT DNAP SARASOTA
dr. ramin mirashemi, a new dnap addition—check this track record!!!!!!!!!!!! http://www.google.com/search?q=Ramin+Mirhashemi&hl=en&lr=&safe=off&start=0&sa=N
dr.jose arena joins dnap scientific advisory board 03 oct 2000 http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=23532
scientific advisory board makeup http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=24575

DNAP COMPARED TO ITS TECHNICAL EQUALS, AND RIVALS:
genomica(gnom)nasdq-ipo29sept00($19)now$22
http://www.bell2bell.newsalert.com/bin/story?StoryId=CoDqtWbWbtKvgmda1&FQ=genomica&HdlFmt=simple&Title=Headlines%20for%3A%20genomica
informax(inunx)nasdq-ipo-03oct00($16)now$23 http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=23532
http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=23552
incite genomics(incy)nasdq $37 http://quicken.excite.com/investments/news/?symbol=INCY
genentech(dna)($172)-2for1split 5 oct00-263million share float---dnap float = 269 million http://www.bell2bell.newsalert.com/bin/digest?Symbol=DNA&

DNAP IN EUROPE http://www.8ung.at/zockstocks http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=21485
http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=24168

WHERE IS DNAP LOCATED—HOW DO YOU GET THERE?
great air fare rates round trip to sarasota http://leisure.travelocity.com/RealDeals/Details/0,2941,TRAVELOCITY_AIR_449,00.html
dnaps new upscale digs in swinging sarasota, fla http://www.ragingbull.altavista.com/mboard/boards.cgi?board=DNAP&read=21059
motel shopper link for sunny sarasota area http://www.roomsaver.com/roomsaver/city/index.html?state=FL&city=Sarasota
location map of coconut ave digs
http://maps.yahoo.com/py/maps.py?BFCat=&Pyt=Tmap&newFL=Use+Address+Below&addr=900+COCONUT+AVE&csz=SARASOTA%2CFLORIDA%2C+34234&country=us&Get%A0Map=Get+Map

avis rent a car sarasota http://www.avis.com/cgi-bin/maps_and_directions/driving_maps/us_locations/mqinterconnect

INTELLIGENT ADVICE OR BIASED ROT?KNOW THE DIFFERENCE OR HOW TO USE THESE MESSAGE BOARDS
email suspected lying-sham efforts,etc to your federal govt(it,s called the sec) at enforcement@sec.gov http://www.ragingbull.altavista.com/mboard/boards.cgi?board=PCBM&read=132869
get the mob out of microcaps http://www.ragingbull.altavista.com/mboard/boards.cgi?board=PCBM&read=132789
crush naked shorting –stop being screwed without even knowing it—read me http://www.ragingbull.altavista.com/mboard/boards.cgi?board=PCBM&read=132581
suspicious sounding codswallop?? ask them to take the universal basher quiz!!!! http://www.ragingbull.altavista.com/mboard/boards.cgi?board=PCBM&read=132816
dnap has unusually good promise—accounting for the sad fact that were in “basher heaven”-read me http://www.ragingbull.altavista.com/mboard/boards.cgi?board=PCBM&read=132818
sec offers tips on how to avoid scams on the internet—good article http://www.sec.gov/consumer/cyberfr.htm


CONTENTS
1.BACKGROUND
2.FOUNDERS
3.PRODUCTS&SERVICES

1.BACKGROUND

DNAPrint genomics is a young e-biotech company based in southwest Florida. We are developing an informatics platform system that will provide dynamic solutions for disease gene discovery,
genetic predisposition and genetic analysis testing. Our work has real-life application to the germinating field of Personalized Medicine and will help lay the foundation for a brand-new area of
medical research called Phenomics.
The PhenomeSM platform system that we are developing will help identify an individual predisposed to develop cancer before the onset of illness so that lifestyles can be altered and/or
preventative measures taken. It will be used to identify individuals who are incompatible with certain drug treatments before the drugs are prescribed and damage is done. It will be used to tease
out important genetic determinants associated with complex genetic diseases, so that drugs can be developed to target these genes.
Our aim is ambitious. By partnering our platform with biotech/pharma, we will participate in the downstream profits generated from pharmaceutical products our platform has enabled. By
marketing our platform directly to the public, we intend to make comprehensive genotype screening solutions accessible to people all over the world via the internet. Our system will enable a more
holistic approach to using genomics information to improve peoples lives.
The patient of the future will have more information and power than ever imagined. The human genome project, the internet and recent technological advancements all contribute to make this
possible, and we intend to take advantage of these synergies to become the primary conduit for the generation and distribution of personalized genetic information.

The Market
Pharmacogenomics is currently a 1 billion dollar industry and is projected to be a 10 billion dollar industry by the end of 2003. Several billions of dollars have been spent on the human genome
project so far, and an equal amount will likely be spent trying to understand what all of the genomics information means (i.e. bioinformatics, proteomics and phenomics). Genomics is a multi billion
dollar industry world-wide and the market for personalized medicine is expected to exceed $25 billion dollars by 2010. Recently congress has approved a $2.3 billion increase in NIH funding to a
total of $18 billion dollars for the year 2000.

2.FOUNDERS
Tony Frudakis, Ph.D.(tfrudakis@dnaprint.com)
Chief Executive Officer, President and Laboratory Director. Dr. Tony Frudakis is a Phi Beta Kappa, Magna Cumme Laude graduate of the University of California system. He received his doctorate
degree in molecular and cell biology from the University of California Berkeley and has 14 total years of experience as a molecular biologist. Dr. Frudakis' technical experience encompass a range
of areas within biology, including the molecular biology of eukaryotic transcriptional regulation, the creation and study of transgenic animals, the development of novel nucleic acid isolation
techniques and gene discovery protocols, bioinformatics processing and anatomical gene expression profiling. At Corixa Corporation in Seattle, WA he developed several new techniques for RNA
fingerprinting, managed and executed high-throughput gene discovery programs for various cancers and was instrumental in the companies early success in attracting R and D partners. Founding
GAFF biologic in 1998, Dr. Frudakis established a good reputation for high quality DNA sequencing and library construction/screening services, until its evolution into the DNAPrint Genomics that
exists today. In all, his work has resulted in a patent portfolio for over 350 unique genes and 2 products

George Frudakis(gfrudakis@dnaprint.com)
Vice President of Business Affairs. George Frudakis has vast experience with start-up company development. He started and developed a successful multi-component company called GAFF group,
which today enjoys over 15 million dollars annually in revenue. During his life’s work as an entrepreneur and businessman, George has learned how to run and successfully manage the financial
and operational aspects of both small and large companies alike. He is a graduate from the California State University at Long Beach in California.

Myung Ho Kim, Ph.D. Mathematics(mkim@dnaprint.com)
Director of Informatics and Lead Mathemetician. Myung recieved his Ph.D. in Mathematics from the University of Michigan in Ann Arbor in 1988 and M.S. in Mathematics from The Ohio State
University in Columbus Ohio. Most recently, Myung worked on the Ant World Server project supported by DARPA (Defense Advanced Research Progect Agency) and implemented
Kolmogorov-Smirnov tests, linear/nonlinear regression, nonparametric analysis and modeling to a TREC 6 (Text Retrieval Conference) project using SAS, C/C++ and Perl languages. Prior to this,
Myung simulated mathematical modeling for breast tumors and implemented/developed various image processing algorithms. He has served as an Honorary research Fellow in the Department of
Mathematics and Information Science at the University of Auckland, New Zealand and a Visiting Research Scholor in the Department of Mathematics at the University of California at Santa Cruz in
California. Prior to coming to the United States, Myung held the position of Assistant Professor in the Department of Mathematics at Sungkyunkwan University in Soel Korea.

Venkateswarlu Kondragunta, Ph.D. (vkondragunta@dnaprint.com)
Director of Biostatistics. Dr. Kondragunta obtained his Ph.D. in Statistics from the University of Madras, Madras, India. He most recently served as a Postdoctoral Fellow at the Schoolof Public
Health, University of Texas, Houston, TX under the tutelage of Dr. Ranajit Chakraborty, one of the most famous and accomplished genetic mathematicians in the world. His research interests
include variance components, linear regression models, general linear models, design and analysis, discriminant analysis, principal component analysis and statistical genetics. He has taught
courses in Variance Components, Design and Analysis of Experiments and Linear Regression Models and Probability Theory at Concordia University in Montreal, Canada. Dr. Kondragunta is an
accomplished programmer and has amassed considerable experience with implementing statistical genetic ideas into C++, S-plus, FORTRAN (7 years experience) and JAVA code. His most recent
work used the REG, ANOVA, GLM, VARCOMP, CANDISC, CLUSTER, DISCRIM, FACTOR, PRINCOMP and LOGISTIC tools in the SAS computing environment on real and simulated data sets.
A partial list of publications for Dr. Kondragunta include:
Chaubey, Y.P. and K.Venkateswarlu. A numerical study of some robust estimators of variance components in one-way model. International Indian Statistical Association Conference proceedings,
October 10-11, 1998, McMaster University, Hamilton, Canada.
Venkateswarlu, K. K.N.Ponnuswamy, and M.R.Srinivasan. Estimation of variance components based on diallel model. Mathematical Biosciences, V-150, 105-112.
Venkateswarlu, K, and K.N.Ponnuswamy. Estimation of variance components based on bio-model of diallel crosses (balanced). Communications in Statistics (Theory & Methods), Vol-27, 139-152.
Venkateswarlu, K. Estimation of variance components based on diallel model involving maternal and maternal interaction effects. Biometrical Journal, Vol-39, 287-295.

3.PRODUCTS&SERVICES
see dnap web page for a complete description of products & services http://www.dnaprint.com/
SNiPdocTM
High-throughput SNP profiling-To help us with our bottom line, we provide contract SNP profiling services to the drug development community. We call this service our SNiPdocTM service, and it is
targeted towards pharmaceutical companies. Many pharmaceutical companies are seeking to enter into the field of Pharmacogenomics. This new field of study could have a dramatic impact on
overall health care costs in the future. Furthermore, by having access to pharmacogenomics data, pharmaceutical companies can focus their clinical trials on segments of the population that are
genetically receptive to the treatment. Experimental drugs can be targeted to individuals of a particular genotype, and genetic variations shown to underlie a poor-response to a trial drug could be
used as a basis for eliminating the non-responding segment of the trial population from the study. In this way, pharmaceutical companies can reduce drug trial failures and the costs associated
with them. Contracting this work out to service providers is a viable option for many smaller pharmaceutical companies who do not have the volume of work necessary to justify the price of the
equipment and expertise. At DNAPrint Genomics, we offer multiple patient – multiple SNP sampling matricies designed on a custom, semi-custom or predefined basis. We can use our proprietary
PhenomixM databases of medically relevant SNPs (numbering in the thousands of SNPs at present), or design chips for your application de-novo. We will work with your scientists to develop the
experiments from beginning to end, that suit your needs, and we can handle your project from blood/tissue or DNA starting points. Data handling will be customized for each client; data can be
deposited in our secure SNP relational databases system offering you the option of accessing your data over the internet. Alternatively, we can burn and hand-delivered CDs to

 




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