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keithsan
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patent:

Advanced Biotherapy Issued Patent for Treatment of AIDS
Monday March 14, 9:30 am ET


WOODLAND HILLS, Calif.--(BUSINESS WIRE)--March 14, 2005--Advanced Biotherapy, Inc. (OTCBB: ADVB - News) announced today that The United States Patent and Trademark Office has assigned U.S. Patent No. 6,863,890 to the Company for use of antibodies to Tumor Necrosis Factor-alpha (TNF-a), Interferon-Gamma (IFN-g) and Interferon-alpha (IFN-a) for the treatment of HIV infection and AIDS. The patent issued on March 6, 2005.
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Edmond Buccellato, CEO of Advanced Biotherapy, states "we believe that the issuance of this patent now provides the Company with additional patent protection in this therapeutic area by inhibiting overproduction of certain cytokine activity."

Dr. Joseph A. Bellanti, the principal investigator of the 'Company-sponsored' Georgetown Medical University FDA phase I clinical trial, states "Many cytokines are altered in HIV infection contributing to viral replication. Prominent among these is TNF-a. This finding provides further linkage of HIV infection with autoimmune disease both from the standpoint of pathogenesis as well as treatment. IFN-g and TNF-a, which are substantially increased in HIV infection, contribute to the immune pathogenesis. The overproduction of TNF-a has the effect of promoting greater viral replication in AIDS patients and therefore we expect that its removal would decrease viral load and lead to clinical improvement."

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keithsan
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this didnt do much, 54 million O/S though... not sure of float couldn't dig at work. Lots of 4's filed not sure whats going on yet....
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